CellScope.fm._fold_change

CellScope.fm. _fold_change (fea_1 : np.ndarray, fea_2 : np.ndarray, selected_number : int)

The _fold_change function computes the fold change of gene expression between two clusters and selects the top genes with the largest fold changes based on the specified number of genes.

Parameters

• fea_1 (np.ndarray):

  Feature matrix for the first cluster.

• fea_2 (np.ndarray):

  Feature matrix for the second cluster.

• selected_number (int):

  Number of top markers to select.

Return

• marker_indices (ndarray):

  Indices of the top markers based on fold change.

• FC_values (ndarray):

  Fold change values of the selected markers.